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Optimization of therapeutic antibodies

In this review, we have summarized the current landscape of therapeutic antibody optimization for successful development. By engineering antibodies with display technology, computer-aided design and site mutagenesis, various properties of the therapeutic antibody candidates can be improved with the...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Gallolu Kankanamalage, Sachith, Dong, Jianbo, Liu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944496/
https://www.ncbi.nlm.nih.gov/pubmed/33928235
http://dx.doi.org/10.1093/abt/tbab003