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Optimization of therapeutic antibodies
In this review, we have summarized the current landscape of therapeutic antibody optimization for successful development. By engineering antibodies with display technology, computer-aided design and site mutagenesis, various properties of the therapeutic antibody candidates can be improved with the...
Autores principales: | Wang, Bo, Gallolu Kankanamalage, Sachith, Dong, Jianbo, Liu, Yue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944496/ https://www.ncbi.nlm.nih.gov/pubmed/33928235 http://dx.doi.org/10.1093/abt/tbab003 |
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