Beyond Amphiphilic Balance: Changing Subunit Stereochemistry Alters the Pore-Forming Activity of Nylon-3 Polymers

[Image: see text] Amphiphilic nylon-3 polymers have been reported to mimic the biological activities of natural antimicrobial peptides, with high potency against bacteria and minimal toxicity toward eukaryotic cells. Amphiphilic balance, determined by the proportions of hydrophilic and lipophilic su...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Courtney, Kevin C., Huth, Sean W., Rank, Leslie A., Weisblum, Bernard, Chapman, Edwin R., Gellman, Samuel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944571/
https://www.ncbi.nlm.nih.gov/pubmed/33611913
http://dx.doi.org/10.1021/jacs.0c12731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944571/
https://www.ncbi.nlm.nih.gov/pubmed/33611913
http://dx.doi.org/10.1021/jacs.0c12731

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