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Beyond Amphiphilic Balance: Changing Subunit Stereochemistry Alters the Pore-Forming Activity of Nylon-3 Polymers
[Image: see text] Amphiphilic nylon-3 polymers have been reported to mimic the biological activities of natural antimicrobial peptides, with high potency against bacteria and minimal toxicity toward eukaryotic cells. Amphiphilic balance, determined by the proportions of hydrophilic and lipophilic su...
Autores principales: | Liu, Lei, Courtney, Kevin C., Huth, Sean W., Rank, Leslie A., Weisblum, Bernard, Chapman, Edwin R., Gellman, Samuel H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944571/ https://www.ncbi.nlm.nih.gov/pubmed/33611913 http://dx.doi.org/10.1021/jacs.0c12731 |
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