Regulation of connective tissue growth factor expression by miR-133b for the treatment of renal interstitial fibrosis in aged mice with unilateral ureteral obstruction

INTRODUCTION: Renal interstitial fibrosis, an important pathological feature of kidney aging and chronic renal failure, is regulated by mesenchymal stem cells (MSCs). We have previously demonstrated low expression of miR-133b in MSC-derived extracellular vesicles (MSC-EVs) in aged rats. However, miR...

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Detalles Bibliográficos
Autores principales: Cao, Dan, Wang, Yuan, Zhang, Yingjie, Zhang, Yinping, Huang, Qi, Yin, Zhong, Cai, Guangyan, Chen, Xiangmei, Sun, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944614/
https://www.ncbi.nlm.nih.gov/pubmed/33691785
http://dx.doi.org/10.1186/s13287-021-02210-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944614/
https://www.ncbi.nlm.nih.gov/pubmed/33691785
http://dx.doi.org/10.1186/s13287-021-02210-2

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