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In vitro characterization of engineered red blood cells as viral traps against HIV-1 and SARS-CoV-2

Engineered red blood cells (RBCs) expressing viral receptors could be used therapeutically as viral traps, as RBCs lack nuclei and other organelles required for viral replication. However, expression of viral receptors on RBCs is difficult to achieve since mature erythrocytes lack the cellular machi...

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Detalles Bibliográficos
Autores principales: Hoffmann, Magnus A.G., Kieffer, Collin, Bjorkman, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944778/
https://www.ncbi.nlm.nih.gov/pubmed/33723514
http://dx.doi.org/10.1016/j.omtm.2021.03.003