mTOR inhibitor INK128 promotes wound healing by regulating MDSCs

BACKGROUND: Skin wounds in diabetic patients hardly recover. Accumulating evidence has shown that mammalian target of rapamycin (mTOR) pathway and myeloid-derived suppressor cells (MDSCs) are involved in inflammatory-related response. INK128 is a novel mTOR kinase inhibitor in clinical development....

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Detalles Bibliográficos
Autores principales: Li, Yi, Xu, Yujun, Liu, Xinhan, Yan, Xin, Lin, Yue, Tan, Qian, Hou, Yayi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944919/
https://www.ncbi.nlm.nih.gov/pubmed/33691762
http://dx.doi.org/10.1186/s13287-021-02206-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944919/
https://www.ncbi.nlm.nih.gov/pubmed/33691762
http://dx.doi.org/10.1186/s13287-021-02206-y

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