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mTOR inhibitor INK128 promotes wound healing by regulating MDSCs
BACKGROUND: Skin wounds in diabetic patients hardly recover. Accumulating evidence has shown that mammalian target of rapamycin (mTOR) pathway and myeloid-derived suppressor cells (MDSCs) are involved in inflammatory-related response. INK128 is a novel mTOR kinase inhibitor in clinical development....
Autores principales: | Li, Yi, Xu, Yujun, Liu, Xinhan, Yan, Xin, Lin, Yue, Tan, Qian, Hou, Yayi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944919/ https://www.ncbi.nlm.nih.gov/pubmed/33691762 http://dx.doi.org/10.1186/s13287-021-02206-y |
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