Inferring the number and position of changes in selective regime in a non-equilibrium mutation-selection framework

BACKGROUND: Recovering the historical patterns of selection acting on a protein coding sequence is a major goal of evolutionary biology. Mutation-selection models address this problem by explicitly modelling fixation rates as a function of site-specific amino acid fitness values.However, they are re...

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Detalles Bibliográficos
Autores principales: Ritchie, Andrew M., Stark, Tristan L., Liberles, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944921/
https://www.ncbi.nlm.nih.gov/pubmed/33691618
http://dx.doi.org/10.1186/s12862-021-01770-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944921/
https://www.ncbi.nlm.nih.gov/pubmed/33691618
http://dx.doi.org/10.1186/s12862-021-01770-4

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