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Inferring the number and position of changes in selective regime in a non-equilibrium mutation-selection framework
BACKGROUND: Recovering the historical patterns of selection acting on a protein coding sequence is a major goal of evolutionary biology. Mutation-selection models address this problem by explicitly modelling fixation rates as a function of site-specific amino acid fitness values.However, they are re...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944921/ https://www.ncbi.nlm.nih.gov/pubmed/33691618 http://dx.doi.org/10.1186/s12862-021-01770-4 |