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Cytotoxic CD8+ T Cells Expressing CXCR5 Are Detectable in HIV-1 Elite Controllers After Prolonged In Vitro Peptide Stimulation

Antiretroviral therapy (ART) is not curative as HIV-1 persists in long-lived viral reservoirs. Consequently, patients are dependent on life-long drug adherence with possible side effects. To overcome these limitations strategies of a functional cure aim at ART free viral remission. In this study, we...

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Detalles Bibliográficos
Autores principales: Adams, Philipp, Iserentant, Gilles, Servais, Jean-Yves, Vandekerckhove, Linos, Vanham, Guido, Seguin-Devaux, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945035/
https://www.ncbi.nlm.nih.gov/pubmed/33717056
http://dx.doi.org/10.3389/fimmu.2020.622343