Cargando…

Cytotoxic CD8+ T Cells Expressing CXCR5 Are Detectable in HIV-1 Elite Controllers After Prolonged In Vitro Peptide Stimulation

Antiretroviral therapy (ART) is not curative as HIV-1 persists in long-lived viral reservoirs. Consequently, patients are dependent on life-long drug adherence with possible side effects. To overcome these limitations strategies of a functional cure aim at ART free viral remission. In this study, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Adams, Philipp, Iserentant, Gilles, Servais, Jean-Yves, Vandekerckhove, Linos, Vanham, Guido, Seguin-Devaux, Carole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945035/ https://www.ncbi.nlm.nih.gov/pubmed/33717056 http://dx.doi.org/10.3389/fimmu.2020.622343

Ejemplares similares

CD32(+)CD4(+) memory T cells are enriched for total HIV-1 DNA in tissues from humanized mice
por: Adams, Philipp, et al.
Publicado: (2020)

The anti-caspase 1 inhibitor VX-765 reduces immune activation, CD4(+) T cell depletion, viral load, and total HIV-1 DNA in HIV-1 infected humanized mice
por: Amand, Mathieu, et al.
Publicado: (2023)

FHR4‐based immunoconjugates direct complement‐dependent cytotoxicity and phagocytosis towards HER2‐positive cancer cells
por: Seguin‐Devaux, Carole, et al.
Publicado: (2019)

The Envelope Cytoplasmic Tail of HIV-1 Subtype C Contributes to Poor Replication Capacity through Low Viral Infectivity and Cell-to-Cell Transmission
por: Santos da Silva, Eveline, et al.
Publicado: (2016)

HIV-1 Tropism Determination Using a Phenotypic Env Recombinant Viral Assay Highlights Overestimation of CXCR4-Usage by Genotypic Prediction Algorithms for CRRF01_AE and CRF02_AG
por: Mulinge, Martin, et al.
Publicado: (2013)

Correction: HIV-1 Tropism Determination Using a Phenotypic Env Recombinant Viral Assay Highlights Overestimation of CXCR4-Usage by Genotypic Prediction Algorithms for CRRF01_AE and CRF02_AG
por: Mulinge, Martin, et al.
Publicado: (2013)

Multimeric immunotherapeutic complexes activating natural killer cells towards HIV-1 cure
por: Schober, Rafaëla, et al.
Publicado: (2023)

Less Cytotoxic Protoflavones as Antiviral Agents: Protoapigenone 1′-O-isopropyl ether Shows Improved Selectivity Against the Epstein–Barr Virus Lytic Cycle
por: Vágvölgyi, Máté, et al.
Publicado: (2019)

Predominance of the heterozygous CCR5 delta‐24 deletion in African individuals resistant to HIV infection might be related to a defect in CCR5 addressing at the cell surface
por: Arendt, Vic, et al.
Publicado: (2019)

Human CD56(dim)CD16(dim) Cells As an Individualized Natural Killer Cell Subset
por: Amand, Mathieu, et al.
Publicado: (2017)

Vaccine- and Breakthrough Infection-Elicited Pre-Omicron Immunity More Effectively Neutralizes Omicron BA.1, BA.2, BA.4 and BA.5 Than Pre-Omicron Infection Alone
por: Santos da Silva, Eveline, et al.
Publicado: (2023)

Characteristics and spread to the native population of HIV-1 non-B subtypes in two European countries with high migration rate
por: Dauwe, Kenny, et al.
Publicado: (2015)

Adenosine Stimulates the Migration of Human Endothelial Progenitor Cells. Role ofCXCR4 and MicroRNA-150
por: Rolland-Turner, Magali, et al.
Publicado: (2013)

Induction of cytotoxic T lymphocytes by primary in vitro stimulation with peptides
Publicado: (1988)

The use of HIV-1 integration site analysis information in clinical studies aiming at HIV cure
por: Kiselinova, Maja, et al.
Publicado: (2016)

Validation of a SARS-CoV-2 Surrogate Neutralization Test Detecting Neutralizing Antibodies against the Major Variants of Concern
por: Santos da Silva, Eveline, et al.
Publicado: (2023)

Discovery of interesting new polymorphisms in a sugar beet (elite [Formula: see text] exotic) progeny by comparison with an elite panel
por: Pegot-Espagnet, Prune, et al.
Publicado: (2019)

COUP-TFI modifies CXCL12 and CXCR4 expression by activating EGF signaling and stimulates breast cancer cell migration
por: Boudot, Antoine, et al.
Publicado: (2014)

Pre-Omicron Vaccine Breakthrough Infection Induces Superior Cross-Neutralization against SARS-CoV-2 Omicron BA.1 Compared to Infection Alone
por: da Silva, Eveline Santos, et al.
Publicado: (2022)

Diagnostic utility of droplet digital PCR for HIV reservoir quantification
por: Trypsteen, Wim, et al.
Publicado: (2016)

HIV Reservoir Characterization Symposium: 19 September 2016, Ghent, Belgium
por: Malatinkova, Eva, et al.
Publicado: (2017)

Patient-reported outcomes among people living with HIV on single- versus multi-tablet regimens: Data from a real-life setting
por: Degroote, Sophie, et al.
Publicado: (2022)

Rapid viral rebound after analytical treatment interruption in patients with very small HIV reservoir and minimal on‐going viral transcription
por: Pannus, Pieter, et al.
Publicado: (2020)

Can immunotherapy be useful for a « functional cure » of HIV infection?
por: Vanham, Guido
Publicado: (2011)

Mechanism of Peptide Agonist Binding in CXCR4 Chemokine Receptor
por: Pawnikar, Shristi, et al.
Publicado: (2022)

Orthostatic intolerance as a potential contributor to prolonged fatigue and inconsistent performance in elite swimmers
por: Petracek, Lindsay S., et al.
Publicado: (2022)

Digital PCR as a tool to measure HIV persistence
por: Rutsaert, Sofie, et al.
Publicado: (2018)

Emerging PCR-Based Techniques to Study HIV-1 Reservoir Persistence
por: Lambrechts, Laurens, et al.
Publicado: (2020)

Antibiotic and cytotoxic peptides
por: Sewald, Norbert
Publicado: (2012)

Highlights from the HIV Cure and Reservoir Symposium, 11–12 September 2017, Ghent, Belgium
por: Kint, Sam, et al.
Publicado: (2018)

Effects of including sprints during prolonged cycling on hormonal and muscular responses and recovery in elite cyclists
por: Almquist, Nicki Winfield, et al.
Publicado: (2020)

Comparative Effects of Prolonged and Intermittent Stimulation of the Glucagon-Like Peptide 1 Receptor on Gastric Emptying and Glycemia
por: Umapathysivam, Mahesh M., et al.
Publicado: (2014)

Involvement of the CXCR7/CXCR4/CXCL12 Axis in the Malignant Progression of Human Neuroblastoma
por: Liberman, Julie, et al.
Publicado: (2012)

CXCR7 stimulates MAPK signaling to regulate hepatocellular carcinoma progression
por: Lin, L, et al.
Publicado: (2014)

Antigens of Mycobacterium tuberculosis Stimulate CXCR6+ Natural Killer Cells
por: Choreño-Parra, José Alberto, et al.
Publicado: (2020)

Boosted protease inhibitor monotherapy in HIV-infected adults: outputs from a pan-European expert panel meeting
por: Arribas, José R, et al.
Publicado: (2013)

On the whereabouts of SARS-CoV-2 in the human body: A systematic review
por: Trypsteen, Wim, et al.
Publicado: (2020)

Evaluating lncRNA Expression Patterns during HIV-1 Treatment Interruption
por: Schynkel, Tinus, et al.
Publicado: (2023)

CCR6 and CXCR6 Identify the Th17 Cells With Cytotoxicity in Experimental Autoimmune Encephalomyelitis
por: Hou, Lifei, et al.
Publicado: (2022)

Efficient Induction of Antigen-Specific CD8(+) T-Cell Responses by Cationic Peptide-Based mRNA Nanoparticles
por: D’haese, Sigrid, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9ll1qs8sove5jlh97vbfdtq059