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Mitochondrial activity regulates the differentiation of skin-derived mesenchymal stem cells into brown adipocytes to contribute to hypertension

BACKGROUND: Brown adipocytes (BAs) are major components of brown adipose tissue (BAT), which is involved in blood pressure regulation. BAs are derived from multiple progenitors, including PDGFRα(+) adipose-derived stem cells (ASCs). Skin-derived mesenchymal stem cells (S-MSCs) have the capacity to d...

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Detalles Bibliográficos
Autores principales: Xi, Wenda, Chen, Wendong, Sun, Weihong, Li, Xiangxiao, Suo, Zhimin, Jiang, Gonghao, Gao, Pingjin, Li, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945215/
https://www.ncbi.nlm.nih.gov/pubmed/33691786
http://dx.doi.org/10.1186/s13287-021-02169-0