Comparative metabolomics analysis of amphotericin B high-yield mechanism for metabolic engineering

BACKGROUND: The polyene macrocyclic compound amphotericin B (AmB) is an important antifungal antibiotic for the clinical treatment of invasive fungal infections. To rationally guide the improvement of AmB production in the main producing strain Streptomyces nodosus, comparative metabolomics analysis...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Chen, Yu, Jiang, Sheng-Xian, Cai, Xue, Huang, Kai, Liu, Zhi-Qiang, Zheng, Yu-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945361/
https://www.ncbi.nlm.nih.gov/pubmed/33750383
http://dx.doi.org/10.1186/s12934-021-01552-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945361/
https://www.ncbi.nlm.nih.gov/pubmed/33750383
http://dx.doi.org/10.1186/s12934-021-01552-z

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