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Super-Treg: Toward a New Era of Adoptive Treg Therapy Enabled by Genetic Modifications

Regulatory Tcells (Treg) are essential components of peripheral immune homeostasis. Adoptive Treg cell therapy has shown efficacy in a variety of immune-mediated diseases in preclinical studies and is now moving from phase I/IIa to larger phase II studies aiming to demonstrate efficacy. However, hur...

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Detalles Bibliográficos
Autores principales: Amini, Leila, Greig, Jenny, Schmueck-Henneresse, Michael, Volk, Hans-Dieter, Bézie, Séverine, Reinke, Petra, Guillonneau, Carole, Wagner, Dimitrios L., Anegon, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945682/
https://www.ncbi.nlm.nih.gov/pubmed/33717052
http://dx.doi.org/10.3389/fimmu.2020.611638