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Virus vaccines: proteins prefer prolines
Most viral vaccines are based on inducing neutralizing antibodies (NAbs) against the virus envelope or spike glycoproteins. Many viral surface proteins exist as trimers that transition from a pre-fusion state when key NAb epitopes are exposed to a post-fusion form in which the potential for virus-ce...
Autores principales: | Sanders, Rogier W., Moore, John P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945883/ https://www.ncbi.nlm.nih.gov/pubmed/33705704 http://dx.doi.org/10.1016/j.chom.2021.02.002 |
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