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The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction

Mutations in the genes encoding the lysine demethylase 5 (KDM5) family of histone demethylases are observed in individuals with intellectual disability (ID). Despite clear evidence linking KDM5 function to neurodevelopmental pathways, how this family of proteins impacts transcriptional programs to m...

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Detalles Bibliográficos
Autores principales: Belalcazar, Helen M., Hendricks, Emily L., Zamurrad, Sumaira, Liebl, Faith L.W., Secombe, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945993/
https://www.ncbi.nlm.nih.gov/pubmed/33596422
http://dx.doi.org/10.1016/j.celrep.2021.108753