Calcium-sensing receptor promotes calcium oxalate crystal adhesion and renal injury in Wistar rats by promoting ROS production and subsequent regulation of PS ectropion, OPN, KIM-1, and ERK expression

OBJECTIVES: To explore the mechanism of calcium-sensing receptors (CaSRs) during the development of nephrolithiasis. MATERIALS AND METHODS: Wistar rats were treated with ethylene glycol to induce calcium oxalate crystallization, and gadolinium chloride (GdCl(3), an agonist of CaSR) and NPS 2390 (an...

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Detalles Bibliográficos
Autores principales: Li, Xiaoran, Chen, Siyu, Feng, Demei, Fu, Yuqiang, Wu, Huang, Lu, Jianzhong, Bao, Junsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Laboratory Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946014/
https://www.ncbi.nlm.nih.gov/pubmed/33678127
http://dx.doi.org/10.1080/0886022X.2021.1881554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946014/
https://www.ncbi.nlm.nih.gov/pubmed/33678127
http://dx.doi.org/10.1080/0886022X.2021.1881554

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