miR-136 improves renal fibrosis in diabetic rats by targeting down-regulation of tyrosine kinase SYK and inhibition of TGF-β1/Smad3 signaling pathway

OBJECTIVE: To investigate the way that miR-136 regulated spleen tyrosine kinase (SYK) and transforming growth factor-β1 (TGF-β1)/Smad3 signaling pathways on renal fibrosis. METHODS: 100 male SD (Sprague-Dawley) rats were randomly divided into diabetic nephropathy (DN) group, normal control (NC) grou...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Pang, Xinlu, Shang, Wenjun, Feng, Guiwen, Wang, Zhigang, Wang, Junxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946058/
https://www.ncbi.nlm.nih.gov/pubmed/32441195
http://dx.doi.org/10.1080/0886022X.2020.1764854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946058/
https://www.ncbi.nlm.nih.gov/pubmed/32441195
http://dx.doi.org/10.1080/0886022X.2020.1764854

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