Epigenome wide association study of response to methotrexate in early rheumatoid arthritis patients

AIM: To identify differentially methylated positions (DMPs) and regions (DMRs) that predict response to Methotrexate (MTX) in early rheumatoid arthritis (RA) patients. MATERIALS AND METHODS: DNA from baseline peripheral blood mononuclear cells was extracted from 72 RA patients. DNA methylation, quan...

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Detalles Bibliográficos
Autores principales: Gosselt, Helen R., Vallerga, Costanza L., Mandaviya, Pooja R., Lubberts, Erik, Hazes, Johanna M. W., de Jonge, Robert, Heil, Sandra G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946177/
https://www.ncbi.nlm.nih.gov/pubmed/33690661
http://dx.doi.org/10.1371/journal.pone.0247709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946177/
https://www.ncbi.nlm.nih.gov/pubmed/33690661
http://dx.doi.org/10.1371/journal.pone.0247709

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