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Inhibition of anti-viral stress granule formation by coronavirus endoribonuclease nsp15 ensures efficient virus replication

Cytoplasmic stress granules (SGs) are generally triggered by stress-induced translation arrest for storing mRNAs. Recently, it has been shown that SGs exert anti-viral functions due to their involvement in protein synthesis shut off and recruitment of innate immune signaling intermediates. The large...

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Detalles Bibliográficos
Autores principales: Gao, Bo, Gong, Xiaoqian, Fang, Shouguo, Weng, Wenlian, Wang, Huan, Chu, Hongyan, Sun, Yingjie, Meng, Chunchun, Tan, Lei, Song, Cuiping, Qiu, Xusheng, Liu, Weiwei, Forlenza, Maria, Ding, Chan, Liao, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946191/
https://www.ncbi.nlm.nih.gov/pubmed/33635931
http://dx.doi.org/10.1371/journal.ppat.1008690