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Development of a novel in vitro assay to screen for neuroprotective drugs against iatrogenic neurite shortening

This work tries to help overcome the lack of relevant translational screening assays, as a limitation for the identification of novel analgesics for neuropathic pain. Hyperexcitability and neurite shortening are common adverse effects of antiviral and antitumor drugs, leading to neuropathic pain. No...

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Detalles Bibliográficos
Autores principales: Martínez, Antón L., Brea, José, Barro, Mateo, Monroy, Xavier, Merlos, Manuel, Burgueño, Javier, Loza, María Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946280/
https://www.ncbi.nlm.nih.gov/pubmed/33690613
http://dx.doi.org/10.1371/journal.pone.0248139