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Autologous adoptive immune-cell therapy elicited a durable response with enhanced immune reaction signatures in patients with recurrent glioblastoma: An open label, phase I/IIa trial

Glioblastoma multiforme (GBM) is an aggressive malignancy classified by the World Health Organization as a grade IV glioma. Despite the availability of aggressive standard therapies, most patients experience recurrence, for which there are currently no effective treatments. We aimed to conduct a pha...

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Detalles Bibliográficos
Autores principales: Lim, Jaejoon, Park, YoungJoon, Ahn, Ju Won, Sim, JeongMin, Kang, Su Jung, Hwang, Sojung, Chun, Jin, Choi, Hyejeong, Kim, Sang Heum, Chun, Duk-Hee, Sung, Kyoung Su, Kwack, KyuBum, Cho, Kyunggi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946298/
https://www.ncbi.nlm.nih.gov/pubmed/33690665
http://dx.doi.org/10.1371/journal.pone.0247293