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yama, a mutant allele of Mov10l1, disrupts retrotransposon silencing and piRNA biogenesis
Piwi-interacting RNAs (piRNAs) play critical roles in protecting germline genome integrity and promoting normal spermiogenic differentiation. In mammals, there are two populations of piRNAs: pre-pachytene and pachytene. Transposon-rich pre-pachytene piRNAs are expressed in fetal and perinatal germ c...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946307/ https://www.ncbi.nlm.nih.gov/pubmed/33635934 http://dx.doi.org/10.1371/journal.pgen.1009265 |