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PIEZO1 and the mechanism of the long circulatory longevity of human red blood cells
Human red blood cells (RBCs) have a circulatory lifespan of about four months. Under constant oxidative and mechanical stress, but devoid of organelles and deprived of biosynthetic capacity for protein renewal, RBCs undergo substantial homeostatic changes, progressive densification followed by late...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946313/ https://www.ncbi.nlm.nih.gov/pubmed/33690597 http://dx.doi.org/10.1371/journal.pcbi.1008496 |