Cargando…

PIEZO1 and the mechanism of the long circulatory longevity of human red blood cells

Human red blood cells (RBCs) have a circulatory lifespan of about four months. Under constant oxidative and mechanical stress, but devoid of organelles and deprived of biosynthetic capacity for protein renewal, RBCs undergo substantial homeostatic changes, progressive densification followed by late...

Descripción completa

Detalles Bibliográficos
Autores principales: Rogers, Simon, Lew, Virgilio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946313/
https://www.ncbi.nlm.nih.gov/pubmed/33690597
http://dx.doi.org/10.1371/journal.pcbi.1008496