Establishment of a well-characterized SARS-CoV-2 lentiviral pseudovirus neutralization assay using 293T cells with stable expression of ACE2 and TMPRSS2

Pseudoviruses are useful surrogates for highly pathogenic viruses because of their safety, genetic stability, and scalability for screening assays. Many different pseudovirus platforms exist, each with different advantages and limitations. Here we report our efforts to optimize and characterize an H...

Descripción completa

Detalles Bibliográficos
Autores principales: Neerukonda, Sabari Nath, Vassell, Russell, Herrup, Rachel, Liu, Shufeng, Wang, Tony, Takeda, Kazuyo, Yang, Ye, Lin, Tsai-Lien, Wang, Wei, Weiss, Carol D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946320/
https://www.ncbi.nlm.nih.gov/pubmed/33690649
http://dx.doi.org/10.1371/journal.pone.0248348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946320/
https://www.ncbi.nlm.nih.gov/pubmed/33690649
http://dx.doi.org/10.1371/journal.pone.0248348

Ejemplares similares