Ancestral haplotype reconstruction in endogamous populations using identity-by-descent

In this work we develop a novel algorithm for reconstructing the genomes of ancestral individuals, given genotype or sequence data from contemporary individuals and an extended pedigree of family relationships. A pedigree with complete genomes for every individual enables the study of allele frequen...

Descripción completa

Detalles Bibliográficos
Autores principales: Finke, Kelly, Kourakos, Michael, Brown, Gabriela, Dang, Huyen Trang, Tan, Shi Jie Samuel, Simons, Yuval B., Ramdas, Shweta, Schäffer, Alejandro A., Kember, Rachel L., Bućan, Maja, Mathieson, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946327/
https://www.ncbi.nlm.nih.gov/pubmed/33635861
http://dx.doi.org/10.1371/journal.pcbi.1008638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946327/
https://www.ncbi.nlm.nih.gov/pubmed/33635861
http://dx.doi.org/10.1371/journal.pcbi.1008638

Ejemplares similares