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A stable immature lattice packages IP(6) for HIV capsid maturation

HIV virion assembly begins with the construction of an immature lattice consisting of Gag hexamers. Upon virion release, protease-mediated Gag cleavage leads to a maturation event in which the immature lattice disassembles and the mature capsid assembles. The cellular metabolite inositiol hexakispho...

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Detalles Bibliográficos
Autores principales: Mallery, Donna L., Kleinpeter, Alex B., Renner, Nadine, Faysal, K. M. Rifat, Novikova, Mariia, Kiss, Leo, Wilson, Miranda S. C., Ahsan, Bilal, Ke, Zunlong, Briggs, John A. G., Saiardi, Adolfo, Böcking, Till, Freed, Eric O., James, Leo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946374/
https://www.ncbi.nlm.nih.gov/pubmed/33692109
http://dx.doi.org/10.1126/sciadv.abe4716