Selective targeting of the inactive state of hematopoietic cell kinase (Hck) with a stable curcumin derivative

Hck, a Src family nonreceptor tyrosine kinase (SFK), has recently been established as an attractive pharmacological target to improve pulmonary function in COVID-19 patients. Hck inhibitors are also well known for their regulatory role in various malignancies and autoimmune diseases. Curcumin has be...

Descripción completa

Detalles Bibliográficos
Autores principales: Chakraborty, Manas Pratim, Bhattacharyya, Sudipta, Roy, Souryadip, Bhattacharya, Indira, Das, Rahul, Mukherjee, Arindam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946438/
https://www.ncbi.nlm.nih.gov/pubmed/33617879
http://dx.doi.org/10.1016/j.jbc.2021.100449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946438/
https://www.ncbi.nlm.nih.gov/pubmed/33617879
http://dx.doi.org/10.1016/j.jbc.2021.100449

Ejemplares similares