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Selective targeting of the inactive state of hematopoietic cell kinase (Hck) with a stable curcumin derivative

Hck, a Src family nonreceptor tyrosine kinase (SFK), has recently been established as an attractive pharmacological target to improve pulmonary function in COVID-19 patients. Hck inhibitors are also well known for their regulatory role in various malignancies and autoimmune diseases. Curcumin has be...

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Detalles Bibliográficos
Autores principales:	Chakraborty, Manas Pratim, Bhattacharyya, Sudipta, Roy, Souryadip, Bhattacharya, Indira, Das, Rahul, Mukherjee, Arindam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946438/ https://www.ncbi.nlm.nih.gov/pubmed/33617879 http://dx.doi.org/10.1016/j.jbc.2021.100449

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