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Crystal Structure of the Severe Acute Respiratory Syndrome (SARS) Coronavirus Nucleocapsid Protein Dimerization Domain Reveals Evolutionary Linkage between Corona- and Arteriviridae

The causative agent of severe acute respiratory syndrome (SARS) is the SARS-associated coronavirus, SARS-CoV. The nucleocapsid (N) protein plays an essential role in SARS-CoV genome packaging and virion assembly. We have previously shown that SARS-CoV N protein forms a dimer in solution through its...

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Detalles Bibliográficos
Autores principales: Yu, I-Mei, Oldham, Michael L., Zhang, Jingqiang, Chen, Jue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946579/
https://www.ncbi.nlm.nih.gov/pubmed/16627473
http://dx.doi.org/10.1074/jbc.M602107200