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Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD

Although activation of adaptive immunity is a common pathological feature of chronic obstructive pulmonary disease (COPD), particularly during later stages of the disease, the underlying mechanisms are poorly understood. In small airways of COPD patients, we found that localized disruption of the se...

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Detalles Bibliográficos
Autores principales: Richmond, Bradley W., Mansouri, Samira, Serezani, Ana, Novitskiy, Sergey, Blackburn, Jessica B., Du, Rui-Hong, Fuseini, Hubaida, Gutor, Sergey, Han, Wei, Schaff, Jacob, Vasiukov, Georgii, Xin, Matthew K., Newcomb, Dawn C., Jin, Lei, Blackwell, Timothy S., Polosukhin, Vasiliy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946625/
https://www.ncbi.nlm.nih.gov/pubmed/32968197
http://dx.doi.org/10.1038/s41385-020-00344-9