IL-22 receptor signaling in Paneth cells is critical for their maturation, microbiota colonization, Th17-related immune responses, and anti-Salmonella immunity

Interleukin-22 (IL-22) signaling in the intestines is critical for promoting tissue-protective functions. However, since a diverse array of cell types (absorptive and secretory epithelium as well as stem cells) express IL-22Ra1, a receptor for IL-22, it has been difficult to determine what cell type...

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Detalles Bibliográficos
Autores principales: Gaudino, Stephen J., Beaupre, Michael, Lin, Xun, Joshi, Preet, Rathi, Sonika, McLaughlin, Patrick A., Kempen, Cody, Mehta, Neil, Eskiocak, Onur, Yueh, Brian, Blumberg, Richard S., van der Velden, Adrianus W. M., Shroyer, Kenneth R., Bialkowska, Agnieszka B., Beyaz, Semir, Kumar, Pawan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946635/
https://www.ncbi.nlm.nih.gov/pubmed/33060802
http://dx.doi.org/10.1038/s41385-020-00348-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946635/
https://www.ncbi.nlm.nih.gov/pubmed/33060802
http://dx.doi.org/10.1038/s41385-020-00348-5

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