HDAC inhibition potentiates anti-tumor activity of macrophages and enhances anti-PD-L1-mediated tumor suppression

Despite the widespread use of the blockade of immune checkpoints, for a significant number of cancer patients, these therapies have proven ineffective, presumably due to the immunosuppressive nature of the tumor microenvironment (TME). Critical drivers of immune escape in the TME include tumor-assoc...

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Detalles Bibliográficos
Autores principales: Li, Xiaolei, Su, Xiao, Liu, Rui, Pan, Yongsha, Fang, Jiankai, Cao, Lijuan, Feng, Chao, Shang, Qianwen, Chen, Yongjing, Shao, Changshun, Shi, Yufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946638/
https://www.ncbi.nlm.nih.gov/pubmed/33564072
http://dx.doi.org/10.1038/s41388-020-01636-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946638/
https://www.ncbi.nlm.nih.gov/pubmed/33564072
http://dx.doi.org/10.1038/s41388-020-01636-x

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