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HDAC inhibition potentiates anti-tumor activity of macrophages and enhances anti-PD-L1-mediated tumor suppression
Despite the widespread use of the blockade of immune checkpoints, for a significant number of cancer patients, these therapies have proven ineffective, presumably due to the immunosuppressive nature of the tumor microenvironment (TME). Critical drivers of immune escape in the TME include tumor-assoc...
Autores principales: | Li, Xiaolei, Su, Xiao, Liu, Rui, Pan, Yongsha, Fang, Jiankai, Cao, Lijuan, Feng, Chao, Shang, Qianwen, Chen, Yongjing, Shao, Changshun, Shi, Yufang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946638/ https://www.ncbi.nlm.nih.gov/pubmed/33564072 http://dx.doi.org/10.1038/s41388-020-01636-x |
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