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Vacuolin-1 inhibits endosomal trafficking and metastasis via CapZβ

Metastasis is the fundamental cause of cancer mortality, but there are still very few anti-metastatic drugs available. Endosomal trafficking has been implicated in tumor metastasis, and we have previously found that small chemical vacuolin-1 (V1) potently inhibits autophagosome-lysosome fusion and g...

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Detalles Bibliográficos
Autores principales: Ye, Zuodong, Wang, Dawei, Lu, Yingying, He, Yunjiao, Yu, Jingting, Wei, Wenjie, Chen, Chang, Wang, Rui, Zhang, Liang, Zhang, Liangren, Le, Minh T. N., Cho, William C., Yang, Mengsu, Zhang, Hongmin, Yue, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946642/
https://www.ncbi.nlm.nih.gov/pubmed/33564074
http://dx.doi.org/10.1038/s41388-021-01662-3