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Vacuolin-1 inhibits endosomal trafficking and metastasis via CapZβ
Metastasis is the fundamental cause of cancer mortality, but there are still very few anti-metastatic drugs available. Endosomal trafficking has been implicated in tumor metastasis, and we have previously found that small chemical vacuolin-1 (V1) potently inhibits autophagosome-lysosome fusion and g...
Autores principales: | Ye, Zuodong, Wang, Dawei, Lu, Yingying, He, Yunjiao, Yu, Jingting, Wei, Wenjie, Chen, Chang, Wang, Rui, Zhang, Liang, Zhang, Liangren, Le, Minh T. N., Cho, William C., Yang, Mengsu, Zhang, Hongmin, Yue, Jianbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946642/ https://www.ncbi.nlm.nih.gov/pubmed/33564074 http://dx.doi.org/10.1038/s41388-021-01662-3 |
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