Concentration–QTc analysis of quizartinib in patients with relapsed/refractory acute myeloid leukemia

PURPOSE: This analysis evaluated the relationship between concentrations of quizartinib and its active metabolite AC886 and QT interval corrected using Fridericia’s formula (QTcF) in patients with relapsed/refractory acute myeloid leukemia (AML) treated in the phase 3 QuANTUM-R study (NCT02039726)....

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Detalles Bibliográficos
Autores principales: Kang, Dongwoo, Ludwig, Elizabeth, Jaworowicz, David, Huang, Hannah, Fiedler-Kelly, Jill, Cortes, Jorge, Ganguly, Siddhartha, Khaled, Samer, Krämer, Alwin, Levis, Mark, Martinelli, Giovanni, Perl, Alexander, Russell, Nigel, Abutarif, Malaz, Choi, Youngsook, Yin, Ophelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946665/
https://www.ncbi.nlm.nih.gov/pubmed/33415416
http://dx.doi.org/10.1007/s00280-020-04204-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946665/
https://www.ncbi.nlm.nih.gov/pubmed/33415416
http://dx.doi.org/10.1007/s00280-020-04204-y

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