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Selective cytotoxicity of epidithiodiketopiperazine DC1149B, produced by marine-derived Trichoderma lixii on the cancer cells adapted to glucose starvation

The core of solid tumors is characterized by hypoxia and a nutrient-starved microenvironment and has gained much attention as targets of anti-cancer drugs. In the course of search for selective growth inhibitors against the cancer cells adapted to nutrient starvation, epidithiodiketopiperazine DC114...

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Detalles Bibliográficos
Autores principales: Tang, Rui, Kimishima, Atsushi, Ishida, Ryosuke, Setiawan, Andi, Arai, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946679/
https://www.ncbi.nlm.nih.gov/pubmed/31435860
http://dx.doi.org/10.1007/s11418-019-01357-w