GASC1 promotes hepatocellular carcinoma progression by inhibiting the degradation of ROCK2

Hepatocellular carcinoma (HCC) is a devastating malignancy without targeted therapeutic options. Our results indicated that the histone demethylase GASC1 signature is associated with later tumor stage and poorer survival in HCC patients. GASC1 depletion led to diminished HCC proliferation and tumor...

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Detalles Bibliográficos
Autores principales: Shao, Na, Cheng, Jiamin, Huang, Hong, Gong, Xiaoshan, Lu, Yongling, Idris, Muhammad, Peng, Xu, Ong, Belinda X., Zhang, Qiongyi, Xu, Feng, Liu, Chungang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946911/
https://www.ncbi.nlm.nih.gov/pubmed/33692332
http://dx.doi.org/10.1038/s41419-021-03550-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946911/
https://www.ncbi.nlm.nih.gov/pubmed/33692332
http://dx.doi.org/10.1038/s41419-021-03550-w

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