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Mutation analysis using cell-free DNA for endocrine therapy in patients with HR+ metastatic breast cancer

We prospectively evaluated the utility of ESR1 and PIK3CA mutation analysis with cell-free DNA (cfDNA) using droplet digital PCR (ddPCR) for the efficacy of endocrine therapy (ET) in hormone receptive positive (HR+) metastatic breast cancer (MBC) patients. CfDNA was analyzed just before the start of...

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Detalles Bibliográficos
Autores principales: Sim, Sung Hoon, Yang, Han Na, Jeon, Su Yeon, Lee, Keun Seok, Park, In Hae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946916/
https://www.ncbi.nlm.nih.gov/pubmed/33692409
http://dx.doi.org/10.1038/s41598-021-84999-9