Typing FGFR2 translocation determines the response to targeted therapy of intrahepatic cholangiocarcinomas

Chromosomal translocations involving fibroblast growth factor receptor 2 (FGFR2) gene at the breakpoints are common genetic lesions in intrahepatic cholangiocarcinoma (ICC) and the resultant fusion protein products have emerged as promising druggable targets. However, predicting the sensitivity of F...

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Detalles Bibliográficos
Autores principales: Pu, Xiaohong, Ye, Qing, Cai, Jing, Yang, Xin, Fu, Yao, Fan, Xiangshan, Wu, Hongyan, Chen, Jun, Qiu, Yudong, Yue, Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946919/
https://www.ncbi.nlm.nih.gov/pubmed/33692336
http://dx.doi.org/10.1038/s41419-021-03548-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946919/
https://www.ncbi.nlm.nih.gov/pubmed/33692336
http://dx.doi.org/10.1038/s41419-021-03548-4

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