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Mucosal Nanoemulsion Allergy Vaccine Suppresses Alarmin Expression and Induces Bystander Suppression of Reactivity to Multiple Food Allergens

We have demonstrated that intranasal immunotherapy with allergens formulated in a nanoemulsion (NE) mucosal adjuvant suppresses Th2/IgE-mediated allergic responses and protects from allergen challenge in murine food allergy models. Protection conferred by this therapy is associated with strong suppr...

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Detalles Bibliográficos
Autores principales: Farazuddin, Mohammad, Landers, Jeffrey J., Janczak, Katarzyna W., Lindsey, Hayley K., Finkelman, Fred D., Baker, James R., O’Konek, Jessica J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946984/
https://www.ncbi.nlm.nih.gov/pubmed/33717078
http://dx.doi.org/10.3389/fimmu.2021.599296