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Estimating hepatitis B virus cccDNA persistence in chronic infection(†)

Hepatitis B virus (HBV) infection is a major global health problem with over 240 million infected individuals at risk of developing progressive liver disease and hepatocellular carcinoma. HBV is an enveloped DNA virus that establishes its genome as an episomal, covalently closed circular DNA (cccDNA...

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Detalles Bibliográficos
Autores principales: Lythgoe, Katrina A, Lumley, Sheila F, Pellis, Lorenzo, McKeating, Jane A, Matthews, Philippa C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947180/
https://www.ncbi.nlm.nih.gov/pubmed/33732502
http://dx.doi.org/10.1093/ve/veaa063