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Quercetin-Conjugated Superparamagnetic Iron Oxide Nanoparticles Protect AlCl(3)-Induced Neurotoxicity in a Rat Model of Alzheimer’s Disease via Antioxidant Genes, APP Gene, and miRNA-101

Alzheimer’s disease (AD) is a neurodegenerative disease with cognitive impairment. Oxidative stress in neurons is considered as a reason for development of AD. Antioxidant agents such as quercetin slow down AD progression, but the usage of this flavonoid has limitations because of its low bioavailab...

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Detalles Bibliográficos
Autores principales: Amanzadeh Jajin, Elnaz, Esmaeili, Abolghasem, Rahgozar, Soheila, Noorbakhshnia, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947204/
https://www.ncbi.nlm.nih.gov/pubmed/33716639
http://dx.doi.org/10.3389/fnins.2020.598617