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Alternatively Splicing Interactomes Identify Novel Isoform-Specific Partners for NSD2

Nuclear receptor SET domain protein (NSD2) plays a fundamental role in the pathogenesis of Wolf–Hirschhorn Syndrome (WHS) and is overexpressed in multiple human myelomas, but its protein–protein interaction (PPI) patterns, particularly at the isoform/exon levels, are poorly understood. We explored t...

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Detalles Bibliográficos
Autores principales: Wang, Weidi, Chen, Yucan, Zhao, Jingjing, Chen, Liang, Song, Weichen, Li, Li, Lin, Guan Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947288/
https://www.ncbi.nlm.nih.gov/pubmed/33718354
http://dx.doi.org/10.3389/fcell.2021.612019