Activation of α7-nAChRs Promotes the Clearance of α-Synuclein and Protects Against Apoptotic Cell Death Induced by Exogenous α-Synuclein Fibrils

Misfolding and abnormal aggregation of α-synuclein (αSyn) have been shown to increase the risk of developing Parkinson's disease (PD). Finding some way to reduce the aggregation of αSyn is particularly important for the treatment of PD. The main route in prion-like αSyn spreading is the choline...

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Detalles Bibliográficos
Autores principales: Zhao, Jifeng, Li, Yun, Li, Yan, Xu, Shi, Tao, Tingting, Hua, Ye, Zhang, Ji, Fan, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947362/
https://www.ncbi.nlm.nih.gov/pubmed/33718373
http://dx.doi.org/10.3389/fcell.2021.637319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947362/
https://www.ncbi.nlm.nih.gov/pubmed/33718373
http://dx.doi.org/10.3389/fcell.2021.637319

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