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Triptolide inhibits epithelial-mesenchymal transition phenotype through the p70S6k/GSK3/β-catenin signaling pathway in taxol-resistant human lung adenocarcinoma

BACKGROUND: Chemotherapy is one of the primary treatments for both small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC), however, chemoresistance develops over time and is a bottleneck to effective chemotherapy worldwide. Therefore, the development of new potent therapeutic agents to...

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Detalles Bibliográficos
Autores principales: Tian, Yu, Li, Peiwei, Xiao, Zhaohua, Zhou, Jie, Xue, Xia, Jiang, Ning, Peng, Chuanliang, Wu, Licun, Tian, Hui, Popper, Helmut, Poh, Mau-Ern, Marcucci, Fabrizio, Zhang, Chengke, Zhao, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947389/
https://www.ncbi.nlm.nih.gov/pubmed/33718039
http://dx.doi.org/10.21037/tlcr-21-145