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Prognostic and predictive effect of KRAS gene copy number and mutation status in early stage non-small cell lung cancer patients

BACKGROUND: In the current analysis, we characterize the prognostic significance of KRAS mutations with concomitant copy number aberrations (CNA) in early stage non-small cell lung cancer (NSCLC), and evaluate the ability to predict survival benefit from adjuvant chemotherapy. METHODS: Clinical and...

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Detalles Bibliográficos
Autores principales: Fung, Andrea S., Karimi, Maryam, Michiels, Stefan, Seymour, Lesley, Brambilla, Elisabeth, Le-Chevalier, Thierry, Soria, Jean-Charles, Kratzke, Robert, Graziano, Stephen L., Devarakonda, Siddhartha, Govindan, Ramaswamy, Tsao, Ming-Sound, Shepherd, Frances A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947394/
https://www.ncbi.nlm.nih.gov/pubmed/33718025
http://dx.doi.org/10.21037/tlcr-20-927